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[DOI] [PMC free article] [PubMed] [Google Scholar] 24.Trevaskis J.L., Griffin P.S., Wittmer C., Neuschwander-Tetri B.A., Brunt E.M., Dolman C.S., Erickson M.R., Napora J., Parkes D.G., Roth J.D

Dietary management should follow the principles of nutritional balance, limiting energy intake and adjusting dietary structure

None of them evaluated the quality of evidence for outcomes by the GRADE assessment

At the same time, patients with long-lasting disease (maximum duration 35 years) were not excluded from the study, suggesting that oral semaglutide may also be a therapeutic choice in patients with longer disease evolution

Weight regain after treatment ends Without sustainable habits in place, appetite often returns once medication stops, increasing the risk of regaining lost weight