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In this case, however, the findings were supported by a randomized, placebo-controlled study of liraglutide in subjects with diabetes who showed a clinically and statistically significant reduction in PAI-1 (25%, from a baseline of 31.4 28.4 U/ml) and a statistically significant reduction in CRP (20%, from a baseline of 4.2 4.2 mg/l), but no change in TNF-alfa or IL-6 (225)

Labs are recommended but not required

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Amongst SGLT2-I, canagliflozin specifically has raised concerns about risk of bone fracture, although it is unclear whether an association exists with other SGLT2-I

The FDA Removes Semaglutide from the Drug Shortage List Reprinted with permission from Birmingham Medical News The Food and Drug Administration (FDA) has removed semaglutide from its drug shortage list after the agency determined the current supply of the drug can meet present and future demand

Hair shedding linked to GLP-1 use is usually telogen effluvium, a temporary shift in the hair growth cycle that often improves once weight stabilizes and nutrient needs are met