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Highmark and AHN studied GLP-1 drugs versus bariatric surgery for people with severe obesity

In participants with obesity and chronic kidney disease without diabetes, once-weekly administration of semaglutide 2.4mg led to a reduction in albuminuria, body weight and systolic blood pressure compared with placebo, with no changes to creatinine or cystatin-C estimated glomerular filtration rate or measured glomerular filtration rate during the 24-week follow-up period.

high confidence of evidence), and fasting plasma glucose concentrations (3.12 mmol/L (3.59 to 2.66), 97.2%

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