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GLP-1 users showed a 49% higher risk for vitamin D deficiency compared to people on SGLT2 inhibitors and a 32% higher risk compared to those on DPP-4 inhibitors

Onions, another common ingredient in Mexican cuisine, can also be problematic for individuals with FODMAP sensitivities

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Findings from this study were supported by another study in which the cascade of hypertension- induced vascular injury was mitigated by the use of liraglutide and a dipeptidyl peptidase-4 inhibitor to prevent the endogenous degradation of GLP-1, linagliptin

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Reported complications described in some GLP-1 drug claims have included: Severe or persistent gastrointestinal symptoms , such as ongoing nausea, vomiting, or abdominal pain Delayed stomach emptying (gastroparesis) , which has been described by some individuals as involving bloating, nausea, vomiting, or difficulty tolerating food Intestinal complications , including reduced bowel activity (ileus), which may involve abdominal discomfort, cramping, or vomiting Gallbladder-related conditions , such as gallstones or gallbladder inflammation Blood-clot-related conditions , including deep vein thrombosis or pulmonary embolism, described in some reports and legal filings Vision-related problems , including reports involving non-arteritic anterior ischemic optic neuropathy (NAION) discussed in connection with semaglutide in certain contexts Not everyone who takes a GLP-1 medication experiences these issues, and the relationship between GLP-1 drugs and reported complications continues to be evaluated in legal proceedings
