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Whether you're already taking one or considering both, heres what to know about how they work, why theyre sometimes prescribed together, and how they compare

When to Startand When Not To According to the package insert, GLP-1 therapy for obesity is indicated for individuals with a BMI 27 with a weight-related condition, or a BMI 30 alone

57% with semaglutide 1.0 mg and 29% with placebo)

Type 2 diabetes mellitus (T2DM) is one of the major subtypes of DM, and its pathogenesis is more complex, involving insulin resistance and insulin secretion dysfunction (Xourafa et al., 2024)

Skin The skin around the breasts is especially prone to stretching, and can lose its youthful elasticity once the fat beneath it has reduced, leaving looser, less supportive skin behind

Some psoriasis treatments, particularly biologics, affect the immune system in ways that could interact with semaglutide