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In studies with rodents, tirzepatide caused thyroid tumors, including thyroid cancer

Some potentially more severe side effects than Wegovy have been reported with Mounjaro, such as kidney and heart issues and an increased risk of some cancers

The way adverse event reporting works is not as strong for these products

Importantly, the largest reductions in BMI were observed in the southern United States, which also reported the highest rates of GLP-1 RA dispensing claims (Rader et al., 2024), a geographic concordance that is consistent with a causal contribution of these pharmacotherapies to the observed population-level BMI decline

Triple agonist of GLP-1 + GIP + GLUCAGON: three key hormones that work synergistically to transform your metabolism

The AMPK pathway in fatty liver disease
