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Constipation is a shared struggle for both IBS-C sufferers and individuals on GLP-1 medications

for example, weight loss associated with the use of GLP-1 RAs in people without cancer may be associated with the prevention of obesity-related cancers

This meta-analysis evaluates their effects on mortality and hospitalization in HFpEF

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While newly approved pharmacotherapies such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) show efficacy, their clinical utility remains constrained by dose-dependent gastrointestinal complications, underscoring the urgent need for safer alternatives

research use only GLP-1 (Glucagon-Like Peptide-1) is a synthetic incretin peptide studied for its potential role in pancreatic beta-cell signaling, glucose-dependent insulin secretion, and hypothalamic appetite regulation pathways
