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These include: Nausea (the most common complaint, particularly in the first few weeks) Vomiting Diarrhoea or constipation Decreased appetite (which, while therapeutically desirable, can occasionally be excessive) Abdominal discomfort or bloating Injection-site reactions (such as redness, itching, or mild swelling at the injection site) Headache, dizziness, and fatigue , particularly during early treatment These effects are generally dose-dependent and tend to diminish as the body adjusts to the medication

Contact your GP if you experience increased urination with excessive thirst, unexplained weight loss, pain or burning when urinating, cloudy or bloody urine, or symptoms of dehydration, as these may indicate inadequate diabetes control or other conditions requiring investigation

The route and mechanism of action determine how your body processes the compound

How often should I be monitored for drug interactions

Foods to Limit or Avoid During Semaglutide Treatment High-fat foodsfried items, creamy sauces, bacon, and fatty cuts of meattrigger nausea in most semaglutide users

Most patients regain weight after stopping GLP-1 medications, with clinical trials showing approximately two-thirds of lost weight returns within one year