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Literature data indicate that PWS patients have lower birth weight and a higher prevalence of preterm delivery and SGA ( Thyroid disorders are quite common in these individuals, and the dysregulation of the hypothalamic-pituitary-thyroid axis is the most frequent cause ( Supplementary Table 1 )

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If severe neuroglycopenia has developed (defined as not being able to consume oral carbohydrates safely as a result of confusion or loss of consciousness), then glucagon can be administered by family members