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Milder DA, et al

Risk increases dramatically with cumulative dosing over weeks without medical oversight or in patients with impaired kidney function

Target 1.21.6 g of protein per kg of body weight daily during active weight loss, or an absolute target of 80120 g/day for adherence

GLP-1 agonists may initially reduce sexual desire, or the ability to orgasm

A March 2021 study on semaglutide, published in The New England Journal of Medicine, showed that people who took the medication lost an average of 14.9% of their body weight in about a year, compared with 2.4% in the placebo group

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