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While some initial GI side effects like nausea may start to improve, you will likely notice more pronounced appetite shifts

In people with male genitalia, decongestants can also constrict the prostate, which surrounds the urethra, also making it more difficult to pass urine, Varin adds

Monitor blood glucose in patients with diabetes Acute Kidney Injury Due to Volume Depletion: There have been postmarketing reports of acute kidney injury, in some cases requiring hemodialysis, in patients treated with semaglutide

But the experience of GLP-1 users is revealing something deeper

Notably, there was a decrease in the cumulative incidence of severe albuminuria in individuals diagnosed with type 1 diabetes in the 1980s compared with those diagnosed in the 1970s in Finland, although no further improvement was apparent in the 19901999 diagnosis cohort [4]

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