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Description
About 1 in 11 adults worldwide have diabetes mellitus, 90% of whom have type 2 diabetes mellitus(T2DM) (Zheng et al., 2018)
GLP-1 RAs also improve glucose uptake and utilization, ensuring energy stability even in metabolically challenged neurons (92)
With GLP-1 medications: You pharmacologically reduce the dopamine-seeking behavior the food noise quiets but because the same pathways handle all reward and motivation non-food joys can get quieter too
Nausea, vomiting, dyspepsia and diarrhea are common side effects
The FDA has warned against unapproved compounded GLP-1 drugs, highlighting risks like dosing errors and contamination
In vitro (cAMP production functional assay), hybrid 24 was found to be equally potent to semaglutide (Supplementary Fig
