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Several GLP-1 receptor agonists have demonstrated cardiovascular benefits in outcome trials

Novo Nordisk's Wegovy pill, the first and only oral GLP-1 for weight loss in adults, now broadly available across America

A meta-regression analysis of GLP-1RA CVOT showed that the magnitude of HbA1c lowering, but not body weight (BW) loss, was associated with the prevention of renal outcomes [24]
Thus, identifying new drug targets and developing more effective and safer treatments is necessary to achieve optimal management of type 2 diabetes

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