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Nevertheless, therapy should be individualized, with careful monitoring for possible ketosis and gastrointestinal adverse effects. Al Ozairi and le Roux said randomized controlled trials are needed to examine the efficacy of GLP-1s among adults with type 1 diabetes

Gastrointestinal side effects have been the most reported, but the safety of higher doses over extended periods needs further investigation

Diabetes Obes Metab (2013) 15(7):593606.10.1111/dom.12050 77 ShirakiAOyamaJKomodaHAsakaMKomatsuASakumaMet alThe glucagon-like peptide 1 analog liraglutide reduces TNF-alpha-induced oxidative stress and inflammation in endothelial cells

That approach is understandable, but it fragments data across notes, apps, and memory, making it hard to see patterns such as injection timing, hydration dips, or protein gaps

Pharmacotherapy for obesity management in adults: 2025 clinical practice guideline update

However, the results vary from person to person