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Lu, S.-C

However, up to 89% of participants taking efinopegdutide experienced gastrointestinal adverse events (mostly nausea, vomiting and diarrhoea) relative to 28% taking placebo and 60% taking liraglutide (86)

Statistical analysis We used cumulative incidences and cause specific hazard regression to estimate hazard ratios (HR) and 95% confidence intervals (CI) for risk of suicide and suicide attempts in GLP-1 RA users vs SGLT-2 inhibitor users or DPP-4 inhibitor users, taking death as a competing risk to suicide into account

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The pharmacologic effects of GLP-1 are noted in the next figure

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