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Researchers note that the 12mg cohort had not reached a weight loss plateau at 48 weeks, suggesting efficacy may continue to increase with longer exposure

Early initiation of the medication, within one year of a cirrhosis diagnosis, resulted in a significant decrease and delay in the need for transplantation further stressing their benefit. She added that the findings address a gap in evidence for patients with MASH cirrhosis who do not have diabetes, and advocate for a shift towards earlier and more proactive therapeutic intervention

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34 These studies suggest that the impact of lifestyle interventions on breast cancer recurrence may be mediated by effective weight loss and adherence, and importantly, even modest weight change can be associated with meaningful clinical benefit

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The medication's effect on blood glucose control is particularly relevant, as elevated glucose levels can create an environment conducive to certain types of infections, including fungal overgrowth