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doi: 10.1016/s0140-6736(23)01127-3, PMID: [DOI] [PubMed] [Google Scholar] 34
Like other weight loss drugs, tirzepatide promotes weight loss by affecting certain brain chemicals involved in food intake, energy expenditure, and fat deposition

Contact your GP or call 111 for medical advice if this occurs

This is not the medication causing gainit is insufficient dosing allowing normal hunger to return

Jensen EP, Mller S, Hviid AV, Veedfald S, Holst JJ, Pedersen J, rskov C, Sorensen CM

Clinical biomarker studies have produced heterogeneous associations between circulating irisin levels and indices of metabolic health, exercise capacity, and bone density across different populations, with effect sizes and directions varying by sex, age, and comorbidity status (Perakakis et al., 2017)
