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[6] [7] People with pre-existing retinopathy should be monitored appropriately
The expansion of EAT enhances pericardial mechanical constraints on the heart, increasing ventricular interdependence and increasing intracavitary pressure under equivalent filling pressures [32]

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However, targeted microbiome support, particularly with strains that have been studied in the context of metabolic health (such as Akkermansia muciniphila and butyrate-producing bacteria like Clostridium butyricum), may offer benefits by supporting gut barrier function and helping the digestive system adapt
