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Prevention strategies include maintaining adequate protein intake (minimum 80-100g daily), taking biotin supplements (2,500-5,000mcg daily), avoiding crash dieting on top of medication effects, and ensuring sufficient iron and zinc intake

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Food and Drug Administration (FDA) approved 68Ga-gozetotide and 18F-piflufolastat PET-CT for the initial staging of patients with prostate cancer and suspicion of metastatic disease, and for the evaluation of potential recurrence based on an elevated posttreatment PSA.[10,11] 18F-fluciclovine PET-CT 18F-fluciclovine PET-CT showed low sensitivity but high specificity in the initial lymph nodal staging of intermediate- and high-risk prostate cancer, compared with PLND.[12-14] Compared with conventional imaging, its specificity was similar, but sensitivity was higher for detection of extraprostatic disease.[14] 18F-fluciclovine also detected more bone metastases and was more sensitive and specific than 99mTc-MDP bone scan.[15] The FDA approved 18F-fluciclovine PET-CT for the assessment of suspected recurrent disease in men with a rising posttreatment PSA

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AG is known to stimulate hunger, and studies have shown that a high AG/UAG ratio is associated with hyperphagia and obesity in individuals with PWS [35,36]