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Still, medications like retatrutide represent an exciting evolution in medical weight loss," says Burns, "but sustainable success comes from a comprehensive strategy that includes nutrition, exercise and a healthy lifestyle.

Some even lost a few more pounds without losing muscle

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Common Antidepressants: Safety Profile With Semaglutide SSRIs such as sertraline, fluoxetine, and paroxetine are among the most widely prescribed antidepressants, and clinical evidence shows they combine safely with GLP-1 medications including semaglutide

By November 2023, CNN had connected compounded semaglutide to at least 100 hospitalizations and 10 deaths