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The SUMMIT trial demonstrated that treatment with tirzepatide reduced the risk of a composite of cardiovascular-related deaths or worsening heart failure, compared with placebo, and improved the health of patients with heart failure with preserved ejection fraction and obesity [147]

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Long-term success will depend on clinical differentiation, real-world evidence, payer value, patient support programs, adherence tools, physician education, and clear positioning across obesity, type 2 diabetes, cardiovascular risk and metabolic syndrome

Consistent fluid intake is one of the simplest protective habits

For example, in a study from the Journal of the American Medical Association , patients achieved around 5.9% loss of their total body weight in three months

The MRO system exists precisely to prevent people from losing jobs or facing adverse action due to legitimate prescription medication use