gila monster and glp-1 🦎 One of the world's most talked-about medicines owes a lot to… a venomous lizard. Researchers studying the saliva of the discovered a molecule similar to GLP-1. That discovery helped Science's 2023 Breakthrough: GLP-1R Agonists

Kotagal V, Albin RL, Mller ML, Koeppe RA, Frey KA, Bohnen NI

In absolute dollar terms, the brands rebate may be larger, even though its net price after rebate may be higher than the biosimilars net price

Additionally, this study utilized information on morbidities and medication from officially maintained registers for administrative purposes, providing a reliable source of data, without relying on selfreporting

Indeed, a significant linear relationship between cortical A and -synuclein has been described in a subgroup of PD, 7,9 in line with experimental studies demonstrating that these proteins may promote and cross-seed one anothers aggregation

Finally, a retrospective cohort study compared 1775 matched pairs of SGLT2i users and nonusers with SLE and type 2 diabetes from the TriNetX database and found that use of SGLT2i was associated with significantly reduced risk of lupus nephritis, dialysis, kidney transplant, heart failure, and all-cause mortality compared with no SGLT2i use 8 9,10

It does not provide dosing advice, dose-change recommendations, missed-dose medical instructions, or injection technique guidance