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Side effects reach their maximum intensity during dose escalation

Methylene blue has antimicrobial properties, so it's sometimes found in medications and home remedies

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However, translation into humans proved disappointing

The PDAC desmoplastic stroma is abundant in extracellular matrix (ECM) deposition, cancer-associated fibroblasts (CAFs), and disorganized endothelium, characterized by insufficient anti-tumoral response [11, 13, 14]

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