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Semaglutide can modestly lower LDL, triglycerides, and raise HDL while supporting weight loss and health

Longitudinal Targeted Minimum Loss-based Estimation, a method that adjusts for both baseline and time-varying confounding, was used to estimate absolute risks of cardiovascular outcomes under sustained use of GLP1-RA and DPP 4i (active comparator), adjusting for baseline and time-varying confounding

Research shows semaglutide can support weight loss in older adults, though efficacy and tolerability vary by individual health status, medication interactions, and metabolic factors

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