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doi:10.1016/j.clnesp.2020.04.010 Wu L, Xia M, Duan Y, et al
Those with GIPR variants favoring dual-agonist response may be better candidates for tirzepatide or GLP-Squared combination therapy

Clinician-guided personalization: Each program is described as overseen by licensed medical providers who personalize dosing and follow-up based on individual needs

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Some people may require an additional dose increase to 1 mg once weekly to achieve optimal glycemic control
Thyroid function often declines during extended caloric restriction as the body attempts to conserve energy
