jp morgan glp 1 GLP-1 Drug Market: the rapid growth of the diabetes and obesity drugs market Infographic Review】2026 J.P. Morgan Healthcare

Figure 9 shows some effects of GLP-1 in the pathophysiology of depression

GLP-1 medications such as Ozempic, Wegovy, and Zepbound are producing significant weight loss in many patients

So motivated to keep going

They reduce systemic inflammation , improve adipokine balance, and restore gut barrier function [24] Better pain and physical-function outcomes in osteoarthritis, and reduced flares in patients with rheumatoid arthritis on DMARDs, pointing to dual cardiometabolic and anti-inflammatory benefits.[28][42] Overall, the integration of GLP-1RA into the treatment of autoimmune diseases has yielded partial improvements in disease control and significant benefits in managing metabolic comorbidities. This does not remove the requirement for standard immunotherapies

Makary has an interest in Sesame, we believe his views on compounded GLP-1s may be different than those of the current FDA administrators, and we find it interesting that this announcement was made before Dr

Treatment deintensification may also be needed in the setting of weight loss and/or optimization of lifestyle behaviors, when fewer pharmacologic agents are needed to maintain A1C goals