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Explore how GLP-1 medications like Ozempic and Wegovy can impact fertility, ovulation and reproductive health for those trying to conceive.

### Funding Statement SDL and AC were supported by the National Science Foundation (Grant Nos.\ CAREER DMS-1944574 and DMS-2325258) ### Author Declarations I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained

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Notably, no permanent treatment discontinuations or dose reductions due to gastrointestinal side effects were reported in ribupatide-treated participants

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In addition, activating GLP-1R reduced Iba-1, IL-1 and TNF- release and inhibited TNC microglial number and morphological changes (process retraction) following nitroglycerin administration