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This pain characteristically develops suddenly, remains constant rather than cramping, and worsens after eating

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In humans, we have recently shown that the GLP-1 RA dulaglutide tends to reduce fluid intake and lowers 24-hour urinary output in healthy volunteers (24)

2013, 108 (4): 365-10.1007/s00395-013-0365-x

Previous antiobesity medications showed modest efficacy with limited long-term safety data and limited benefits beyond weight loss
