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In addition, trials on human and mice showed GLP-1 receptor agonists benefits in heart failure, endothelial lining and,myocardial ischemia.First, heart failure clinical trials on human showed at New York Heart Association involved diabetic patients with stage 3-4 heart failure better response with Glp-1 continuous infusion over 12 weeks duration in the form of better left ventricular ejection fraction and 6 minute walk over 48 hours trial of GLP-1 infusion in nondiabetic patients with stage 2-3 heart failure

24 As a result, there is a reduction in the atherosclerotic plaques macrophage-associated inflammation

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McGill et al., Long-Term Efficacy and Safety of Linagliptin in Patients With Type 2 Diabetes and Severe Renal Impairment, Diabetes Care, vol

The decision to use a compounded drug is guided by the licensed prescribing clinician's medical judgment based on a telehealth consultation and medical history