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Description
The main molecular mechanisms of GLP-1RA in obesity reduction include the increased production of insulin by the cAMP/PKA pathway in pancreatic -cells, along with an augmented translocation of GLUT-4 in the cellular membrane for improved glucose homeostasis, and energy expenditure by lipolytic cycle stimulation

A 2022 warning letter from the Office of Prescription Drug Promotion (OPDP) highlighted an Instagram ad posted by the company that reportedly made, false or misleading claims and representations about the benefits and risks of Trulicity. It found that the company minimized the risks and overemphasized the benefits of the drug

We still need more long-term data to understand the full impact of GLP-1s on fertility, hormone balance, and metabolic health in PCOS

Some had progressive loss of vision

Lets discuss! (Source: @ Curios VC) #obesity #glp #biotech #biopharma Informative

Methods Data sources and search strategy This systematic review was conducted up to 01 December 2024 in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement guidelines
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