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These benefits may outweigh the risks and side effects of medication or surgery
Sitagliptin, anagliptin, gemigliptin, and teneligliptin form class 3 of the DPP-4 inhibitors (see Figure 2) (13, 14)

The market will likely continue to grow due to the rising rate of obesity, the increasing prevalence, and the factors mentioned above

Step Therapy and Formulary Tiers Several BCBS affiliates impose step therapy for Zepbound

Clinical studies on GLP-1s often show double-digit percentage weight loss, whereas berberine studies typically show more modest results, often around 3% to 5% of body weight
