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[117] demonstrated that dapagliflozin provides direct cardiac protection by suppressing the NHE1/mitogen-activated protein kinase/activator protein-1 pathway-mediated inflammatory response in cardiomyocytes, reducing proinflammatory macrophage infiltration in the cardiac tissue of HF mice

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[DOI] [PubMed] [Google Scholar] 56.Tchero H, Kangambega P, Briatte C, Brunet-Houdard S, Retali G-R, Rusch E

Setting a calendar reminder or associating the injection with a consistent weekly activity supports adherence over months and years of treatment

It is also used as a weight management drug in people with type 2 diabetes