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As a synthetic GLP-1 analog sharing approximately 94% sequence homology with native human GLP-1, semaglutide retains the biological activity of the endogenous hormone while incorporating structural modifications that enhance resistance to enzymatic degradation and prolong systemic exposure [2]

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STAT News cited a recently published British Medical Journal review of 37 studies, tallying an aggregate of more than 9,300 participants, in which approximately 50% of the people who started on the drugs stop taking them within one year

Ongoing mechanistic and clinical research will determine whether these agents possess inherent reproductive benefits or primarily facilitate fertility through systemic metabolic restoration

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