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Dose-response effects on HbA1c and bodyweight reduction of survodutide, a dual glucagon/GLP-1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial

10.1523/JNEUROSCI.3579-15.2016 262

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Because exenatide restores the normal first-phase insulin release that is lost in people with diabetes, it should be injected before meals to successfully suppress hepatic glucose production1)
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