new glp-1 drug Diabetes Patients Also Struggle to Access Agonists GLP-1 Medications for Weight Loss:

Whether you're searching for a way to outsmart diabetes or seeking a solution for stubborn weight gain, look no further: A hormone called GLP-1 (glucagon-like peptide 1) has a powerful ability to lower blood sugar and melt unwanted pounds

J Manag Care Spec Pharm

In a 12-week phase 2a study, individuals with obesity were treated with weekly doses of 4 mg, 6 mg, or placebo

doi: 10.1016/S2213-2600(19)30198-5, 2

Unlike existing peptide predecessors that are digested by stomach acid unless armored with absorption enhancers, orforglipron is a chemicala small molecule designed to survive the GI tract and activate the GLP-1 receptor directly

Under hyperglycaemic conditions they additionally inhibit glucagon secretion