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Under physiological conditions, the gutliver axis helps maintain metabolic homeostasis and immune balance

5Not included in the prespecified testing hierarchy for controlling type-I error

Nevertheless, individual patient factorssuch as other medical conditions, additional medications, and personal tolerancemust be carefully considered

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In the second study, the Authors investigated also changes in the clinical expression of hyperandrogenism, but they failed to find any effects on the Ferriman Gallwey (FG) score, probably due the short duration of the study (26 weeks) [64]
A regulatory submission is under review in Japan
