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Regular follow-up with the diabetes care team, including monitoring of HbA1c, renal function, and cardiovascular risk factors, is essential to ensure that glycaemic targets are achieved and that any new treatment is well tolerated

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This was predominantly driven by the continuing roll-out of Novo Nordisks semaglutide and Lillys tirzepatide, and off-label use of their respective T2D-indicated brands

Fourth, the large sample sizes across the outcome cohorts provided adequate precision of effect estimates, and agent-specific analyses helped clarify whether associations were consistent across different GLP-1RA medications