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10.1074/jbc.M113.452516 269 YadavV

Project administration: RGL, ETF, LMPG

GLP-1 receptor agonist injections, such as Mounjaro and Wegovy, are supported by robust clinical evidence, demonstrating 15-25% weight loss in trials

Consensus recommendations on utilizing glucagon-like peptide-1 (GLP-1) receptor agonists in the treatment of type 2 diabetes mellitus

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While enteral administration offers several advantages over other routes of drug delivery in terms of convenience, promoting medication compliance, it faces several obstacles, of which the most widely recognized are inefficient absorption owing to physical barriers and an acidic microenvironment, along with degradation by proteases and the first-pass metabolism in the liver