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Due to their effectiveness, GLP-1-based medicines have become fundamental in obesity pharmacotherapy, with current investigations into next-generation multi-agonists (e.g., retatrutide) aimed at improving results [39]

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The genetic assessment reveals genetic predispositions in peptide signalingnot exact medication response or travel resilience

Endpoints in clinical trials on NAFLD and NASH Key point Determining optimal yet feasible endpoints for clinical trials evaluating pharmacologic agents for NAFLD and NASH is complicated by slow progression of clinically significant outcomes

10.7759/cureus.32610