glp 1 agonist and pregnancy Preconception use of GLP-1 GLP-1/GIP receptor agonists for obesity treatment GLP-1 weight-loss drugs pose hidden

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doi: 10.1007/s40120-022-00350-y 34 BarbierPZejneliOMartinhoMLasorsaABelleVSmet-NoccaCet al

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At 180 days follow-up, death (HR 1.10, 95% CI 0.572.14) and heart failure rehospitalization (HR 1.30, 95% CI 0.891.88) did not differ compared with those in the placebo group

Finally, the combination of a GLP-1 receptor agonist and amylin agonism by cagrilintide/semaglutide is currently under investigation (Table 1)

Whether these kidney actions of amylin and related molecules are relevant to DKD remains to be ascertained