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Unlike prior reports of fasting beyond 21 days in non-obese individuals [11, 12], this case demonstrates substantial weight loss (125 pounds) accompanied by improvements in depression, anemia, hypoxia/hypercapnia, functional status, and left ventricular (LV) mass

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While this falls within ranges seen with other weight loss interventions, it raises questions about optimizing the quality of weight loss for those particularly concerned about muscle preservation

Goals: Aiming to reach and maintain a weight between 175-185 lbs

Cobenfys approval was supported by data from three registrational trials in which the drug showed benefit in treating schizophrenia on the Positive and Negative Syndrome Scale

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