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Description
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Wegovy and Ozempic are given as a weekly injection under the skin

Semaglutide's approved dosing schedule involves gradual increases over 16 weeks, starting at 0.25 mg weekly and titrating to 2.4 mga protocol designed to improve tolerability and clinical outcomes

Clinical takeaways Our biological framework proposes a potential mechanism by which serotonergic circuitry may underlie an association between GLP-1 agonist medications and a decrease in sexual desire
Its proposed mechanism of action includes stimulation of glucose-dependent insulin secretion, suppression of glucagon (via GLP-1), enhanced lipid metabolism (via GIP), and increased energy expenditure (via glucagon receptor activation)

doi: 10.1021/jacs.3c09078
