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Double-blind placebo-controlled studies have found that women who take GnRH agonists for endometriosis have an increased incidence of depressive mood symptoms

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Across 24 pooled trials with treatment durations from 3 to 12 months, reductions in lean body mass clustered in the 14% range modest, by that metric

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Diabetes Res Clin Pract 2014;106:567575