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doi: 10.3233/JAD-180584 239 TaiJLiuWLiYLiLHolscherC

A notable impediment to drug development is the lack of biomarkers that could be used to demonstrate target engagement for many of the mechanistic pathways that might be targetable to prevent or treat AD/ADRD

This study suggests a slightly increased risk of a rare but serious eye condition among people with type 2 diabetes starting GLP-1 receptor agonists compared with those starting SGLT-2 inhibitors or DPP-4 inhibitors

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The more you shock your body, the more it goes into panic mode, and when youre losing 30% of your body weight in 12 weeks, thats a crisis metabolically. With HU6, Khan explained, were able to increase our patients metabolism in modest ways, but that over the treatment durations lead to fat-specific weight loss that is very meaningful. Trial participants taking HU6 have lost three to four pounds per monthconsistently, Dallas said