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10.1038/mp.2012.141 23 HarastaA

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In pancreatic -cells [58] and ischaemic coronary vascular cells [59], activating GLP-1R promoted mitochondrial respiration, while in astrocytes, GLP-1R activation suppressed mitochondrial oxidative phosphorylation stimulated by -amyloid peptides [60]
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Multiple clinical trials studying over a dozen therapies failed to show improvement in visual outcomes for NAION patients, with surgical interventions showing no benefit and potentially causing harm
