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These agents function by mimicking the actions of endogenous GLP-1, a hormone that is secreted by the gut in response to food intake [1, 2]

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Regulatory Status: advantage goes to Tirzepatide

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- Reduction in liver fat and improvements associated with metabolic liver disease (MASLD/MASH) in a Phase 2a study

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Figure 2 3.1.1 Cancer-associated fibroblasts (CAFs) TME includes not only immune cells but also stromal cells, and CAFs are the main stromal cell type in the TME

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