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Daily injection with the weight-loss drug liraglutide was more effective than placebo (both combined with lifestyle interventions) at reducing weight in children 612 years of age with obesity.

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Beyond these metabolic benefits, accumulating evidence indicates that GLP-1RAs exert immunomodulatory effects, including suppression of pro-inflammatory cytokines, enhancement of regulatory T-cell function, and improvements in adipose tissue and gut-derived immune signaling

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