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Jiaqi Zhang, Jiake Mo, et al

In recent years, the effects of GLP-1 agonists/analogues on the CNS have gained relevance due to emerging evidence supporting the neuroprotective effects of these molecules

Cagrilintide activates amylin receptors (calcitonin receptor/RAMP complexes) in the area postrema and nucleus of the solitary tract a circumventricular organ that allows circulating peptides to access central neurons directly

The fifth reviewed GLP-1 treatments for type 2 diabetes, and none of the treatments studied were sublingual

2024 March 2024;384:q642

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