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Description
GLP-1 medications may cause gastrointestinal symptoms, such as: Nausea Vomiting Diarrhea Constipation These tend to happen most often when increasing doses, but usually improve over time
The Dual Agonist: Tirzepatide Tirzepatide targets two distinct nutrient-stimulated hormone pathways: GLP-1 (Glucagon-Like Peptide-1): Activates receptors in the brain to delay gastric emptying, induce early satiety, and reduce central appetite signals
10.1016/j.metabol.2016.03.009 [DOI] [PMC free article] [PubMed] [Google Scholar] FDA FaDA Highlights of prescribing information - OZEMPIC (2020)
In addition to some safety concerns, weight regain is one of the biggest issues critics voice in using drugs like Ozempic and Wegovy for weight loss
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54:3427-3434 [PubMed: 16306358] 141
