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Unnikrishnan, CEO and Chief of Endocrinology at Chellaram Diabetes Institute, Pune, said, Oral semaglutide has shown it can reduce the risk of major adverse cardiovascular events (MACE), regardless of whether participants were already using sodium-glucose cotransporter-2 inhibitors (SGLT2i)

After first use, the pen can be kept at room temperature (below 30C) or in the refrigerator for up to six weeks

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The initial tirzepatide dose in both cohorts was 2.5 mg, which was increased by 2.5 mg every 4 weeks to a maximum final dose of 10.0 mg at week 16 (Cohort 1) or 15.0 mg at week 24 (Cohort 2)